Stanford scientists published a paper on Jan. 25 in the journal Science Translation Medicine that found that those with the flushing gene variant might have a higher risk of heart disease.

“We found mice carrying this variant have impaired vascular dilatation,” Joseph Wu, director of the Stanford Cardiovascular Institute and co-author of the study, told The Daily Beast in an email.

The authors discovered that people who participated in the new study and had ALDH2*2 suffered from impaired vascular function—even after just modest alcohol consumption or “one standard drink,” Wu said.

The researchers discovered that a diabetes drug dubbed empagliflozin seemed to have a nullifying effect on the symptoms in cultured human cells.

“However, our studies showed that empagliflozin may potentially be used as a preventative measure against vascular diseases, especially in high-risk patient cohort such as ALDH2*2 carriers who drink excessively,” he explained.

So, in the meantime, it’s important to remember that line from all those beer commercials and drink responsibly—especially if you glow red as a beet when you knock back a few.