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For The First Time, CRISPR Gene-Editing Has Been Used on Squid - ScienceAlert
Aug 08, 2020 50 secs
For the first time, the innovative CRISPR gene editing method has been used on squid, marking a milestone in the scientific study of these creatures – and opening up many new areas of potential research.

In this case CRISPR-Cas9 genome editing was used on Doryteuthis pealeii (the longfin inshore squid) to disable a pigmentation gene, turning off the pigmentation usually found in the squid eye and inside specialised skin cells called chromatophores.

The longfin inshore squid is of huge interest to scientists, and studies of Doryteuthis pealeii going as far back as the 1950s have helped to make significant contributions to the field of neuroscience – including the first description of the nerve impulse.

Being able to edit genes in these creatures is a major new development, and one which could see squid join the ranks of model organisms in genetic research, such as fruit flies and zebrafish.

It's hoped that because these squid are masters at editing their own genetic code, this research could push our own techniques even further.

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