Goodbye Pandemic, Hello Endemic - The Epoch Times
Jan 16, 2022 1 min, 32 secs
In order for Omicron to be the last wave, it needs to be able to stimulate strong and long-lasting immunity against potential future variants.

The hope for long-lasting immunity relies on protective T cell responses.

In my previous article I quoted a University of Cape Town study showing that long-lasting T cell response, induced either by vaccination or natural infection, cross-recognizes Omicron.

The authors concluded that well-preserved T cell immunity to Omicron is likely to contribute to protection from severe COVID-19 caused by other variants.

10, the scientific journal Nature published a peer-reviewed article titled “Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts.” Submitted to Nature by Imperial College London scientists five months ago, the article looked at T cell epitopes (very small protein fragments) from different SARS-CoV-2 proteins (S, N, E, and ORF1) in terms of their cross-reactivity to those of other species of human coronavirus OC-43 and HKU1, which cause the common cold.

In other words, if the N-protein epitopes from the common cold could induce long-term protective T cell immunity against SARS-CoV-2, then Omicron infection with plenty of N-protein epitopes should also be able to induce similar T cell immunity and provide stronger protection against any future SARS-CoV-2 variant infections.

There are two reasons that the transition from pandemic to endemic did not happen until Omicron: 1) all the widely used vaccines are based on the spike protein, which does not induce protective long-lasting T cell response, and 2) natural immunity was not widespread.

Accordingly, we could foresee that a wider spread of Omicron infection would induce a wider range of cross-reactive T cell immunity, subsequently offering more widespread protection against potential future SARS-CoV-2 variants.

Hopefully, Omicron will act like its other attenuated vaccine cousins, and with any luck no other SARS-CoV-2 variants will emerge and become a pandemic in the future.

1. Watch Live as Boeing’s Starliner Capsule Attempts First ISS Docking - Gizmodo
May 20, 2022 # politics 46 secs
2. Taylor Swift's boyfriend Joe Alwyn gushes over her 'amazing' honorary doctorate degree from NYU - Daily Mail
May 19, 2022 # politics 1 min, 0 secs
3. NASA Suspends ISS Spacewalks Because Its Spacesuits Are Leaking Water - Gizmodo
May 19, 2022 # science 51 secs
4. Biden missing an opportunity to send a strong message to China: Victoria Coates
May 19, 2022 # breaking 2 secs
5. Med student discovers she has cancer during class on cancer screening - Insider
May 16, 2022 # health 27 secs
6. You don't have to do cardio for weight loss, resistance training as effective - Insider
May 16, 2022 # health 45 secs
7. John Fetterman, Pennsylvania lieutenant governor running for Senate, suffers stroke - CBS News
May 15, 2022 # politics 42 secs
8. Former NASA leaders praise Boeing’s willingness to risk commercial crew - Ars Technica
May 16, 2022 # science 1 min, 24 secs
9. Buffalo shooting: Black Americans describe grief and fear
May 16, 2022 # breaking 1 min, 14 secs
10. Russian soldier Vadim Shishimarin accused of war crimes pleads guilty to killing unarmed Ukrainian civilian - CBS News
May 19, 2022 # politics 50 secs
11. Updated PGA Championship 2022 Odds & Picks for Jordan Spieth, Rory McIlroy, Justin Thomas, More - The Action Network
May 19, 2022 # politics 2 mins, 27 secs
12. Mississippi is the fattest place in America, report shows - Daily Mail
May 17, 2022 # health 2 mins, 16 secs
13. These Videos From a Space Probe Flying Past The Sun Are Truly Out of This World - ScienceAlert
May 19, 2022 # science 1 min, 0 secs
14. Bobby Brown reveals Catholic priest tried to molest him at age 10 - Daily Mail
May 18, 2022 # entertainment 1 min, 44 secs
15. FDA Commissioner: 'Don't Think We Need the Defense Production Act' - 'There Is Formula out There'
May 17, 2022 # breaking 27 secs
16. Ingenious Underwater Drone Can Transition to Flight in Less Than a Second - Gizmodo
May 18, 2022 # science 1 min, 9 secs


Get monthly updates and free resources.


© Copyright 2022 365NEWSX - All RIGHTS RESERVED