The High-Risk, High-Reward Research program, supported by the Common Fund at the National Institutes of Health has awarded 103 new research grants to support highly innovative scientists who propose visionary and broadly impactful meritorious behavioral and biomedical research projects.

The High-Risk, High-Reward Research program supports investigators at each career stage who propose innovative research that, due to their inherent risk, may struggle in the traditional NIH peer-review process despite their transformative potential

The Common Fund oversees programs that pursue major scientific opportunities and gaps throughout the research enterprise, are of significant importance to NIH, and require collaborations across the agency to succeed

The High-Risk, High-Reward Research program manages four awards, including two awards specifically for researchers in the early stages of their careers

NIH issued eight Pioneer awards, 72 New Innovator awards, nine Transformative Research awards, and 14 Early Independence awards for 2022 

Funding for the awards comes from the NIH Common Fund, the National Institute on Aging, the National Institute of General Medical Sciences, the National Institute of Mental Health, and the National Cancer Institute

Common Fund programs are managed by the Office of Strategic Coordination in the Division of Program Coordination, Planning, and Strategic Initiatives in the NIH Office of the Director in partnership with the NIH Institutes, Centers, and Offices

About the National Institutes of Health (NIH):

NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S