Results from cell culture experiments show that commercially available preparations have an effect on Sars-Cov-2 viruses.

The use of mouthwashes that are effective against Sars-Cov-2 could thus help to reduce the viral load and possibly the risk of coronavirus transmission over the short term.

The results of the study are described by the team headed by Toni Meister, Professor Stephanie Pfänder and Professor Eike Steinmann from the Bochum-based Molecular and Medical Virology research group in the Journal of Infectious Diseases, published online on July 29, 2020.

They mixed each mouthwash with virus particles and an interfering substance, which was intended to recreate the effect of saliva in the mouth.

They then used Vero E6 cells, which are particularly receptive to Sars-Cov-2, to determine the virus titer.

In order to assess the efficacy of the mouthwashes, the researchers also treated the virus suspensions with cell culture medium instead of the mouthwash before adding them to the cell culture.

Three mouthwashes reduced it to such an extent that no virus could be detected after an exposure time of 30 seconds.

The Bochum group is examining the possibilities of a clinical study on the efficacy of mouthwashes on Sars-Cov-2 viruses, during which the scientists want to test whether the effect can also be detected in patients and how long it lasts.

Reference: “Virucidal efficacy of different oral rinses against SARS-CoV-2” by Toni Luise Meister, Yannick Brüggemann, Daniel Todt, Carina Conzelmann, Janis A Müller, Rüdiger Groß, Jan Münch, Adalbert Krawczyk, Jörg Steinmann, Jochen Steinmann, Stephanie Pfaender and Eike Steinmann, 29 July 2020, The Journal of Infectious Diseases.

August 6, 2020

August 6, 2020

August 6, 2020

August 6, 2020

August 6, 2020