As fires burned at multiple places in the city, the College Football Hall of Fame was vandalized, according to the station.

The crowd also spoke out against the deaths of Ahmaud Arbery, fatally shot while he was jogging, and Breonna Taylor, killed by police during a raid of her home.

In the New York City borough of Brooklyn, a police ban was burned as a crowd surrounded it, according to NBC New York.

A crowd tried unsuccessfully to get into the New York Police Department's 88th Precinct in Brooklyn, police said.

At least 50 people have been arrested, a senior New York Police Department official said.

"We have a long night ahead of us in Brooklyn," Mayor Bill de Blasio said on Twitter.

In Detroit, a 19-year-old man was fatally shot amid protests when a suspect in a gray Dodge Durango "pulled up to the location and fired shots into the crowd," police said in a statement.

Nine people were arrested during the demonstrations, Detroit Police Chief James Craig said.

In Minneapolis, where a third night of demonstrations erupted into riots Thursday night, protesters returned to the streets and blocked interstate 35W, according to NBC affiliate KARE

Floyd, 46, was killed after Officer Derek Chauvin put his knee on his neck for more than 8 1/2 minutes after police were called to a report of counterfeit money used at a market