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The Effects of Sleep Debt - The New York Times
Jun 24, 2022 2 mins, 4 secs
Recent studies in humans and mice have shown that late nights and early mornings may cause long lasting damage to your brain.

The review, which canvassed the last couple of decades of research on long term neural effects of sleep deprivation in both animals and humans, points to mounting evidence that getting too little sleep most likely leads to long-lasting brain damage and increased risk of neurodegenerative disorders like Alzheimer’s disease.

“This is really, really important in setting the stage for what needs to be done in sleep health and sleep science,” said Mary Ellen Wells, a sleep scientist at the University of North Carolina, who did not contribute to the review.

It has long been known that intense periods of sleep deprivation are bad for your health.

In the first experimental study of sleep deprivation, published in 1894 by the Russian scientist Maria Manasseina, puppies were forced to stay awake through constant stimulation; they died within five days.

(In 1963, a high school student managed to stay awake for 264 hours.) You can consistently miss out on sleep — chronic sleep deprivation.

Over the past couple of decades, however, the animal research on sleep deprivation has become more nuanced, precise and, possibly, applicable to humans, according to Dr.

In the brains of mice, sleep deprivation led to cell death after a few days of sleep restriction — a much lower threshold for brain damage than previously thought.

After a full year of regular sleep, the mice that previously had been sleep-deprived still suffered from neural damage and brain inflammation.

“It is possible that sleep deprivation damages rat and mouse brains, but that doesn’t mean that you should get stressed about not getting enough sleep,” said Jerome Siegel, a sleep scientist at the University of California, Los Angeles, who did not contribute to the review.

He also expressed concern that undue worry about the long-term effects of sleep deprivation could lead people to try to sleep more, unnecessarily and with medication.

There is currently no ethical way to measure the degree and kind of cell damage caused by sleep deprivation in the locus coeruleus and hippocampus of a living human?

But looking at all of this literature together, of around one week of chronic sleep loss, it really does suggest that you injured the brain to some extent.”.

If a link can be drawn between mice and humans, it could change the way we think about sleep, which is typically in terms of sleepiness rather than neural damage.

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