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This Is What It Means If You Don't Pee Enough, According to Science - msnNOW
Oct 21, 2020 49 secs
Researchers identified a gene, called PIEZO2, which may be responsible for that familiar "urge" that comes with a full bladder.

PIEZO2 appears to work with at least two types of cells in the body to sense when the bladder needs to be emptied.

The gene contains instructions for producing proteins that are activated in response to certain cells in the body being stretched or squeezed–for example, when the bladder fills up.

However, the researchers found that certain people are born with a genetic deficiency in this gene, meaning they have trouble sensing when their bladder is filling up and therefore, feel less of an urge to go to the bathroom.

On top of that, 25 percent reported only peeing once or twice a day, and over 40 percent said that when they finally do feel an urge to go, it comes on abruptly.

Nearly 60 percent of the patients said they had trouble urinating, sometimes needing to press on their lower abdomen in order to go.

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