HAVANA (AP) — The COVID-19 pandemic is sweeping through the leadership of Latin America, with two more presidents and powerful officials testing positive this week for the new coronavirus, adding a destabilizing new element to the region’s public health and economic crises.

Bolivian interim President Jeanine Añez, 53, made her own diagnosis public Thursday, throwing her already troubled political propects into further doubt.

And in Venezuela, 57-year-old socialist party chief Diosdado Cabello said Thursday on Twitter that he, too, had tested positive, at least temporarily sidelining a larger-than-life figure considered the second-most-powerful person in the country.

An Associated Press review of official statements from public officials across Latin America found at least 42 confirmed cases of new coronavirus in leaders ranging from presidents to mayors of major cities, along with dozens, likely hundreds, of officials from smaller cities and towns.

Honduras President Juan Orlando Hernández announced June 16 that he and his wife had tested positive, along with two other people who worked closely with the couple.

Venezuela – already largely cut off to the outside world before COVID-19 – has had far fewer registered cases than many other countries in Latin America, though in recent weeks the number of new confirmed infections has been steadily increasing.

Guatemalan President Alejandro Giammattei placed his entire Cabinet and their staff in quarantine Thursday after one of his ministers tested positive.

In Bolivia, officials said the interim president Añez, had not been been displaying symptoms and was in good spirits in her official residence on Friday.

Añez, who took office after President Evo Morales was ousted during national unrest last year, does not have a vice president and, if she could no longer serve, the next in the line of succession is Senate President Eva Copa, a member of Morales’ party and a bitter opponent of Añez