A paralyzing winter storm wrought havoc with COVID-19 vaccination efforts around the country on Tuesday, forcing the cancellation of appointments and delaying vaccine deliveries just as the federal government rolled out new mass vaccination sites aimed at reaching hard-hit communities.

FEMA opened its first COVID-19 inoculation sites in Los Angeles and Oakland, part of a broader effort by the Biden administration to get shots into arms more quickly and reach minority communities hit hard by the outbreak.

And the administration said Tuesday it was boosting the amount of vaccine sent to states to 13.5 million doses per week, a 57% increase from when President Joe Biden took office nearly a month ago, as well as doubling to 2 million the weekly doses being sent to pharmacies.

Allison Arwady said more than a hundred city vaccine sites didn’t get shipments Tuesday because of the extreme weather, leading to many cancellations.

The Biden administration said the weather was expected to disrupt shipments from a FedEx facility in Memphis and a UPS installation in Louisville, Kentucky.

In Texas, Houston’s Harris County rushed to dispense more than 8,000 doses of Moderna’s coronavirus vaccine after a public health facility lost power early Monday and its backup generator also failed, authorities said.

More than 400,000 additional doses due in Texas now won’t arrive until at least Wednesday, officials said.

Geisinger, one of Pennsylvania’s largest health systems, canceled vaccine appointments scheduled for Wednesday and Friday at several locations after the CDC told state health officials that shipments would be delayed because of severe weather.

The Biden administration plans to establish 100 federally assisted vaccination sites nationwide in cooperation with state authorities.

population, have received at least one dose of the vaccine, and 15 million have gotten both shots, the CDC said.