Christopher Walken (The Dead Zone, Catch Me If You Can), Florence Pugh (Black Widow, Midsommar), and Austin Butler (Elvis) have already been cast as Shaddam IV, Princess Irulan, and Feyd-Rautha Harkonnen, respectively!
As the ruler of the Known Universe, Shaddam conspired with Baron Harkonnen to assassinate Leto Atreides, feeling threatened by the Red Duke's growing popularity.
Though Feyd-Rautha attempted to assassinate his uncle, the Baron forgave him, and the latter remained loyal to him and the Harkonnen name.