While The Andy Griffith Show was certainly a set that produced some genuine and long-lasting friendships, star Andy Griffith was a prankster — and one particular co-star took the brunt of his antics. !

Myron McCormick, Don Knotts, and Andy Griffith in NO TIME FOR SERGEANTS ('58) #TCMEssentials pic.twitter.com/ToTMxn1gRm.

In that time, fans had grown attached to widower town Sheriff Andy Taylor (played by Griffith) and his son Opie as well as Aunt Bee and Deputy Barney Fife.

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Meanwhile, fans might have suspected tensions between Griffith and the actor who portrayed Barney Fife, Don Knotts.

While there may have been a disappointing end to their professional relationship on the set, Griffith and Knotts spent years working together and having a good time